Profluent Bio

Profluent, a frontier AI lab for biology, is seeking a Controller to lead its accounting function, including financial close, technical accounting, equity, treasury, and compliance, as the company scales toward a public-company environment.

Profluent, an AI lab for biology, seeks a Machine Learning Scientist to drive research into pretraining large-scale deep learning models for biomolecular design. The role involves developing state-of-the-art generative models, collaborating with interdisciplinary teams, and shaping ML strategy.

Profluent, an AI lab for biology, seeks an experienced Machine Learning Engineer to build and improve models and ML systems for protein design, including large-scale generative models, pipelines, and infrastructure.

Profluent, a frontier AI lab for biology, seeks a Scientist II to lead the ML Design Evaluation program, bridging ML and experimental biology to generate high-quality data for protein design models. The role involves scoping assays, defining QC standards, and collaborating with ML and protein design teams.

Profluent is seeking a Scientist II to drive mRNA production and process development for customized base editor programs. This hands-on lab role involves synthesis, purification, characterization, and optimization of research-grade mRNA for high-throughput screening and scaled production for mouse studies.

Profluent, an AI lab for biology, seeks a Machine Learning Scientist to drive research on generative models for protein design. The role involves developing state-of-the-art models, collaborating with interdisciplinary teams, and shaping ML strategy. Requires PhD and experience in ML and biology.

Profluent is seeking an Executive Director / VP of Biology & Translational Pharmacology to lead scientific strategy and execution of gene editing therapeutic programs, focusing on liver-directed base editing for metabolic diseases.

Profluent, an AI lab for biology, seeks a Machine Learning Scientist to drive research into reinforcement learning for biomolecular design. The role involves developing state-of-the-art RL algorithms for protein design, collaborating with cross-functional teams, and shaping the ML direction as an early employee.

Profluent is seeking a Scientist II - Sr. Scientist to build and apply experimental workflows for characterizing CRISPR base editing specificity and genomic safety. The role involves developing assays like CHANGE-seq-BE, interpreting NGS data, and collaborating with cross-functional teams to guide editor design and therapeutic development.

Profluent is seeking an Associate Director/Director to lead in vivo pharmacology strategy for base editor therapeutics, overseeing rodent and NHP studies from discovery to IND-enabling. The role involves cross-functional leadership, CRO management, and building scalable pharmacology capabilities.

Profluent is seeking a Senior Software Engineer to design, build, and scale its data platform for protein engineering campaigns. The role involves building secure pipelines, data warehouses, and infrastructure using Python, GCP, BigQuery, and PostgreSQL to enable machine learning and biological discovery.

Profluent, a frontier AI lab for biology, seeks a Biotech Project Manager to orchestrate internal and external programs, building comprehensive timelines across bioinformatics, ML, and wet-lab validation. The role requires 3-5 years of project management experience in biotech, with strong skills in Jira and SmartSheet.

Profluent is seeking a product-minded engineering manager to lead its Lab Informatics Platform team, overseeing software development for scientific data infrastructure, sample tracking, and Benchling integration. The role involves mentoring engineers, architecting systems, and partnering with scientists to accelerate experimental workflows.

Profluent seeks an experienced computational scientist to lead the design and development of NGS analysis pipelines for gene editing and protein design, working at the intersection of computational biology and software engineering.

Profluent, an AI-first protein design company, seeks a scientist with deep expertise in therapeutic antibody development and ML-guided protein design to lead the ML Design Evaluation program. This hands-on technical role bridges ML needs and experimental systems, scoping campaigns, defining assay quality standards, and closing the Design-Build-Test-Learn loop. The position is hybrid in Emeryville, CA.

Profluent is seeking a product-minded engineering manager to lead the Lab Informatics Platform team, managing a small team and building scientist-facing tools for experiment design, sample tracking, and data integration. The role combines engineering management, technical leadership, and product ownership.

Profluent is an AI-first protein design company seeking a Senior Software Engineer to design, build, and scale its data platform for protein engineering campaigns.

Profluent seeks an Associate Director/Director to lead in vivo pharmacology strategy for customized base editor therapeutics. The role involves overseeing rodent and NHP studies, guiding candidate selection, and building in vivo pharmacology capabilities for AI-designed gene editing medicines.

Profluent is seeking a Scientist II to lead mRNA production and process development for customized base editor programs. This hands-on role involves synthesis, purification, and optimization of research-grade mRNA for screening and in vivo studies. The position requires expertise in IVT-based mRNA production and team management.